Zanamivir and oseltamivir bind differently at the neuraminidase catalytic site and this contributes to different drug resistance profiles. 扎那米韦和奥塞米韦结合在神经氨酸酶的不同催化位点,这就导致了这种耐药情况不同的发生。
ADAM-TS9, Catalytic domain, between first and second furin site; Rabbit anti. 催化结构域,第一和第二之间融合位点;兔抗。
Beginning in1991, my colleagues and I had the privilege of working with structural biologists and medicinal chemists to test small chemicals that might intercalate into the catalytic site of the HIV protease, an enzyme essential for the production of infectious progeny virus. 从1991年开始,我的同事和我有幸与结构生物学家和医学化学家合作,对有可能阻隔艾滋病毒蛋白酶的触媒点的微型化学药物进行测试,这种蛋白酶是繁殖传染性病毒的必要酵素。
Advances in the studies on structure of catalytic active site and characteristics of laccase 漆酶催化活性中心结构及其特性研究进展
The catalytic action and active site constitution of fluorinated alumina in the synthesis of β-picoline 经氟处理的氧化铝在合成β-甲基吡啶中的催化作用及活性中心结构
Experimental results indicated that the catalytic activity was correlated closely with the acidity and the dimensional framework of the Bronsted acid site in catalysts. 结果表明:催化剂活性位的Bronsted酸强度和空间结构是影响催化剂活性和选择性的主要因素。
Treatment of NOx by Catalytic and Reducing Method with Metallic Carbon Catalyst and Its Application Case in Shuttle Launching Site 金属碳基催化剂催化还原法治理氮氧化物在航天发射场的应用
We have compared these structures of phospholipase A 2's, explained the results of fluorescent spectrum study on the phospholipase A 2's and calculated the electrostatic potential maps on the catalytic active site. 在此基础上,我们在三维结构水平上解释了磷脂酶A2荧光光谱学研究的一些结果。我们还对四种江浙蝮蛇毒磷脂酶A2的酶活性部位的静电势分布做了分析。
The development trends of fractal geometry in the aspects of quantitative evaluation of the structural sensitivity in catalytic reaction, indentifying active site, property-test of catalyst materials, simulation of the design of the surface appearance of catalyst by computer and catalytic reaction engineering are reviewed. 介绍了分数维几何在定量评估催化反应的结构敏感性、鉴别活性位、催化材料的性能测试、计算机模拟催化剂表面形貌设计及催化反应工程等方面的研究动向。
Thus we suppose that the active center of AChE acts as not only the catalytic site but also one of the antigenic determinants of the enzyme. 乙酰胆碱酯酶的活力中心不仅是酶的催化部位,而且也是酶分子上的一个抗原决定簇。
Treating Exhaust Gas with Catalytic Combustion at Shuttle Site 催化燃烧法在航天发射场废气治理中的应用
Because the catalytic site of a-ALDC has not been certified and the catalytic mechanism has to be also further proved, it is difficult to enhance the enzyme activity in low temperature by the rational design. 由于α-ALDC的活性部位尚未完全确定,催化机理也需进一步证实,在这种条件下通过酶的合理化设计来提高酶在低温下的活力有一定困难。
The embedded surface molecule ( ESM) method is a new systematical approach to describe the active site defined for a heterogeneous catalytic reaction, which considers the active site as a "surface molecule". 嵌入表面分子方法是描述非均相催化反应中所定义的活性中心的新方法。该法是将活性中心看作一个表面分子。
In addition, the catalytic activity of catalyst is also correlative to the coordinating sphere of the active site. 另外,催化剂的活性也受到催化剂活性中心的开放程度的制约。
Three catalytic sites were predicted through bioinformatics analysis. The predicted sites of sorbose dehydrogenase were mutated by fixed point mutation method, a site was mutated into triplet codon coding three amino acids, and the activity of mutant was analyzed. 通过生物信息学分析预测出2个催化位点,通过定点突变方法对各个位点进行了突变,并对突变体做了活性分析。
So we can infer that the tryptophan at the fourteenth site has active effects to the catalytic ability of the protein, but the tyrosine at the 132 site hasn 't. 由此可推断,该蛋白的第14位色氨酸对其催化能力有积极作用,而第132位的酪氨酸对其催化能力没有很大的影响。